2016 CRACK IT Challenges Launch Event

  • NC3Rs
Thursday 08 September 2016 10:30

This year’s NC3Rs CRACK IT Challenges will be launched at an event held on 8 September in central London.

The 2016 CRACK IT Challenges competition consists of four Challenges identified jointly by the NC3Rs and Sponsors. This year the competition is funded by the NC3Rs, co-funding provided by Arthritis Research UK (“Osteo-chip”) and ESPRC (“Osteo-chip” and “Maximise”) and supported by Innovate UK (SBRI) with in-kind contribution from the Sponsors. There are nine Sponsors (Arthritis Research UK, GlaxoSmithKline, MRC Harwell, Roche, Bayer, Merck, Novartis, Syngenta and Dow Agrosciences).

The Challenges are detailed in the Challenge briefs which include a description of the problem to be solved, the 3Rs benefits, the names of the Sponsors and the nature of their proposed in-kind contributions, the notional financial cost of the project (the sum to be awarded by the NC3Rs), the potential timescale of the work and proposals for the organisation of the project. The 2016 Challenges are listed below:

  • Challenge 22 Osteo-chip- An in vitro model to recapitulate the human osteoarthritic joint” (Challenge sponsored by Arthritis Research UK and GSK and co-funded by Arthritis Research UK and EPSRC).
  • Challenge 23 Retinal 3D- A Physiologically-Competent Human Retinal 3D Model” (Challenge sponsored by Roche, Bayer, Merck and Novartis).
  • Challenge 24 EASE- EliminAting Surgical Embryo transfer in mice” (Challenge sponsored by MRC Harwell).
  • Challenge 25Maximise- Maximising confidence whilst minimising data generation for acute hazard classification of mixtures” (Challenge sponsored by Syngenta and Dow Agrosciences and co-funded by EPSRC).

Programme | Registration


A draft agenda can be found here.

The meeting will consist of introductory talks on CRACK IT and open innovation in the current economic landscape.

There will also be Challenge surgeries where Sponsors will introduce their specific Challenge and answer questions from registrants and potential applicants. 

There will be a networking session where delegates have the opportunity to meet potential new collaborators and partners to solve the Challenges.

The launch event is free to attend but registration is essential.


Registration for the 2016 CRACK IT Challenges Launch Event is now closed.


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